Metal Gear Solid 2: Substance does not work on my system (Windows Vista, NVIDIA GeForce 8800 GTS, AMD Athlon 64 X2 4200+, 2 GB RAM) for some reason.

When I press 'Run', it goes full screen but then shows nothing but a black screen.

No button presses seem to register inside the program.

I have to ALT+TAB to quit it.

Any ideas?

I heard that no PC MGS works under Vista ... -_-
I'm sorry for you :(